Brain glioblastoma

Description

brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.

Data source
FinnGen phenocode C3_GBM
Cancer reg: TOPOGRAPHY codes C71
Cancer reg: MORPHOLOGY codes 9440
Level in the ICD-hierarchy C
First defined in version DF2
Ontology
DOID 3073
GWAS catalog 0006545
SNOMED CT 276828006

Key figures

Sex All Female Male
Number of individuals 48 20 28
Unadjusted prevalence (%) 0.04 0.03 0.05
Mean age at first event (years) 65.82 67.83 64.38
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) N/A N/A N/A
Case fatality at 5-years (%) 87.5 90.0 85.71

Associations