Malignant immunoproliferative diseases

Description

Waldenstrom macroglobulinemia: Waldenstrom macroglobulinemia (WM) is an indolent B-cell lymphoproliferative disorder characterized by the accumulation of monoclonal cells in the bone marrow and peripheral lymphoid tissues, and associated with the production of serum immunoglobulin M (IgM) monoclonal protein.

Data source
FinnGen phenocode CD2_IMMUNOPROLIFERATIVE
Hospital Discharge registry ICD-10: C88
Cause of Death registry ICD-10: C88
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 0060901
GWAS catalog 0009441

Key figures

Sex All Female Male
Number of individuals 51 27 24
Unadjusted prevalence (%) 0.04 0.04 0.04
Mean age at first event (years) 66.77 68.55 64.76
Median number of events / individual 5 4 7

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 60.78 55.56 66.67
Case fatality at 5-years (%) 25.49 25.93 25.0

Associations