Idiopathic thrombocytopenic purpura

Description

autoimmune thrombocytopenic purpura: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.

Data source
FinnGen phenocode D3_ITP
Hospital Discharge registry ICD-10: D693, ICD-9: 2873A, ICD-8: 28710
Cause of Death registry ICD-10: D693, ICD-9: 2873A, ICD-8: 28710
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 8924
GWAS catalog 0007160

Key figures

Sex All Female Male
Number of individuals 233 122 111
Unadjusted prevalence (%) 0.18 0.16 0.19
Mean age at first event (years) 50.64 46.62 55.05
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 52.79 51.64 54.05
Case fatality at 5-years (%) 7.3 3.28 11.71

Associations