Diabetic ketoacidosis

Description

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Data source
FinnGen phenocode DM_KETOACIDOSIS
Hospital Discharge registry ICD-10: E121/E1001/E1101/E111/E101/E131/E141
Hospital Discharge registry: exclude ICD-9 E121
Cause of Death registry ICD-10: E131/E1001/E1101/E111/E101/E121/E141
Cause of Death registry: exclude ICD-9 E121
First defined in version DF2
Ontology
DOID 1837
GWAS catalog 1000897
MESH D016883
SNOMED CT 420422005

Key figures

Sex All Female Male
Number of individuals 3071 1485 1586
Unadjusted prevalence (%) 2.32 1.98 2.76
Mean age at first event (years) 32.89 32.44 33.31
Median number of events / individual 2 2 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 22.34 23.77 21.0
Case fatality at 5-years (%) 3.0 2.09 3.85

Associations