Diabetic retinopathy

Description

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Data source
FinnGen phenocode DM_RETINOPATHY
Include DM_BCKGRND_RETINA, DM_BCKGRND_RETINA_NONPROLIF, DM_RETINA_PROLIF, DM_OPHTALMOPAT_PROGRESS, DM_VITREOUS_BLEEDING, DM_NEOVASCULAR_GLAUCOMA, DM_MACULOPATHY, DM_RETINA_NOS, DM_OPTHALMIC_COMORB, DM_EYE_OPER
First defined in version DF2
Ontology
DOID 8947
GWAS catalog 0003770
MESH D003930
SNOMED CT 4855003

Key figures

Sex All Female Male
Number of individuals 6607 3138 3469
Unadjusted prevalence (%) 4.98 4.18 6.04
Mean age at first event (years) 57.42 57.11 57.7
Median number of events / individual 4 4 4

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 64.37 64.37 64.37
Case fatality at 5-years (%) 9.67 7.84 11.33

Associations