Disorders of lipoprotein metabolism and other lipidaemias
Description
familial hypercholesterolemia: Familial hypercholesterolaemia is an autosomal inherited disorder characterized by markedly elevated LDL-cholesterol levels and an increased risk of premature atherosclerotic cardiovascular disease
Data source
| FinnGen phenocode | E4_LIPOPROT |
| Hospital Discharge registry | ICD-10: E78 |
| Cause of Death registry | ICD-10: E78 |
| Include | E4_HYPERCHOL, E4_HYPERGLYCER, E4_HYPERLIPMIX, E4_HYPERCHYLO, E4_HYPERLIPNAS, E4_LIPODEF, E4_LIPOPROTNAS |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 8852 | 4004 | 4848 |
| Unadjusted prevalence (%) | 6.68 | 5.33 | 8.44 |
| Mean age at first event (years) | 62.97 | 64.43 | 61.76 |
| Median number of events / individual | 1 | 1 | 1 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 22.64 | 22.35 | 22.88 |
| Case fatality at 5-years (%) | 5.4 | 4.87 | 5.84 |