Depression

Description

unipolar depression: A mood disorder having a clinical course involving one or more episodes of serious psychological depression that last two or more weeks each, do not have intervening episodes of mania or hypomania, and are characterized by a loss of interest or pleasure in almost all activities and by some or all of disturbances of appetite, sleep, or psychomotor functioning, a decrease in energy, difficulties in thinking or making decisions, loss of self-esteem or feelings of guilt, and suicidal thoughts or attempts.

Data source
FinnGen phenocode F5_DEPRESSIO
Hospital Discharge registry ICD-10: F33/F32, ICD-8: 79020|2980
Cause of Death registry ICD-10: F32/F33, ICD-8: 79020|2980|3004
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 1470, 1595, 2848
GWAS catalog 0003761

Key figures

Sex All Female Male
Number of individuals 13154 8561 4593
Unadjusted prevalence (%) 9.92 11.39 8.0
Mean age at first event (years) 42.68 42.05 43.88
Median number of events / individual 3 3 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 55.7 58.43 50.62
Case fatality at 5-years (%) 2.84 2.04 4.31

Associations