Guillain-Barre syndrome

Description

Guillain-Barre syndrome: Guillain-BarrC) syndrome (GBS) is the term used to describe a spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients. GBS is clinically heterogeneous and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS; see these terms) and some other regional variants.

Data source
FinnGen phenocode G6_GUILBAR
Hospital Discharge registry ICD-10: G610, ICD-8: 35401
Cause of Death registry ICD-10: G610, ICD-8: 35401
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 12842
GWAS catalog 0007292
MESH D020275
SNOMED CT 40956001

Key figures

Sex All Female Male
Number of individuals 137 63 74
Unadjusted prevalence (%) 0.1 0.08 0.13
Mean age at first event (years) 44.72 41.4 47.55
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 43.07 38.1 47.3
Case fatality at 5-years (%) 3.65 1.59 5.41

Associations