Diseases of the myoneural junction and muscle

Description

neuromuscular disease: Any disease that impairs the functioning of the muscles, either directly, being pathologies of the voluntary muscle, or indirectly, being pathologies of nerves or neuromuscular junctions

Data source
FinnGen phenocode G6_MYONEU
Include G6_MYASTHENIA, G6_TOXMYONEU, G6_CONDEVMYA, G6_MYONEUOTHUNS, G6_MUSDYST, G6_MYOTDIS, G6_CONMYOP, G6_MITOCMY, G6_MUSCOTHUNS, G6_DRUGMYOP, G6_ALCOMYOP, G6_MYOPTOX, G6_PERIOPAR, G6_INFLAMYOP, G6_MYOPOTHUNS, G6_MYOMUSCINOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 440
GWAS catalog 1001902
MESH D009468

Key figures

Sex All Female Male
Number of individuals 967 483 484
Unadjusted prevalence (%) 0.73 0.64 0.84
Mean age at first event (years) 56.85 56.35 57.34
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 33.92 34.78 33.06
Case fatality at 5-years (%) 14.37 12.42 16.32

Associations