Disorders of choroid and retina

Description

retinopathy of prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Data source
FinnGen phenocode H7_CHOROIDRETINA
Include H7_CHORIORETINFLAM, H7_CHOROIDOTH, H7_RETINALDETACH, H7_RETINAVASC, H7_RETINALDISOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 13025
GWAS catalog 1001158
MESH D012178
SNOMED CT 415297005

Key figures

Sex All Female Male
Number of individuals 9305 4836 4469
Unadjusted prevalence (%) 7.02 6.44 7.78
Mean age at first event (years) 59.66 60.2 59.07
Median number of events / individual 2 2 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 56.51 54.26 58.94
Case fatality at 5-years (%) 5.43 4.92 5.97

Associations