Nail disorders

Description

Yellow Nail Syndrome: Yellow nail syndrome (YNS) is a very rare syndromic disorder characterized by the variable triad of characteristic yellow nails, chronic respiratory manifestations, and primary lymphedema.

Data source
FinnGen phenocode L12_NAILDIS
Hospital Discharge registry ICD-10: L60/L62
Cause of Death registry ICD-10: L60/L62
Include L12_NAIL_INGROW, L12_NAIL_LYSIS, L12_NAIL_GRYPHOSIS, L12_NAIL_DYSTROPHY, L12_NAIL_BEAULINES, L12_NAIL_YELLOW, L12_NAILNAS, L12_NAILINOTH
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 0050468
GWAS catalog 1001452
MESH D056684
SNOMED CT 400211001

Key figures

Sex All Female Male
Number of individuals 640 340 300
Unadjusted prevalence (%) 0.48 0.45 0.52
Mean age at first event (years) 44.64 49.79 38.81
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 21.25 27.35 14.33
Case fatality at 5-years (%) 2.97 2.94 3.0

Associations