Viral infections of the central nervous system

Description

viral meningitis: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)

Data source
FinnGen phenocode AB1_VIRAL_CNS
Hospital Discharge registry ICD-10: A89/A84/A87/A85/A82/A81/A88/A83/A80/A86, ICD-9: 071/046/063/045/062/047/048/064/049, ICD-8: 04[0-3]|06[2-5]|071
Cause of Death registry ICD-10: A86/A82/A81/A88/A80/A89/A83/A87/A85/A84, ICD-9: 048/064/049/071/046/063/045/062/047, ICD-8: 04[0-3]|06[2-5]|071
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 10310
GWAS catalog 1001236
MESH D008587
SNOMED CT 58170007

Key figures

Sex All Female Male
Number of individuals 594 367 227
Unadjusted prevalence (%) 0.45 0.49 0.4
Mean age at first event (years) 41.43 39.61 44.38
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 10.44 10.35 10.57
Case fatality at 5-years (%) 5.39 2.72 9.69

Associations