Colon adenocarcinoma


colon adenocarcinoma: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.

Data source
FinnGen phenocode C3_COLON_ADENO
Cancer reg: TOPOGRAPHY codes C18
Cancer reg: MORPHOLOGY codes 8140
Level in the ICD-hierarchy C
First defined in version DF2
DOID 234
GWAS catalog 1001949

Key figures

Sex All Female Male
Number of individuals 763 359 404
Unadjusted prevalence (%) 0.58 0.48 0.7
Mean age at first event (years) 66.64 65.99 67.22
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) N/A N/A N/A
Case fatality at 5-years (%) 24.51 23.4 25.5