Carcinoma in situ of breast, other/unspecified

Description

ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

Data source
FinnGen phenocode CD2_INSITU_BREAST_NOS
Sex specific endpoint 2
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 0060074, 8791
GWAS catalog 0000432
MESH D002285

Key figures

Sex All Female Male
Number of individuals 87 85 N/A
Unadjusted prevalence (%) 0.07 0.11 N/A
Mean age at first event (years) 57.26 58.12 N/A
Median number of events / individual 1 1 N/A

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 31.03 31.76 N/A
Case fatality at 5-years (%) 2.3 2.35 N/A

Associations