Multiple myeloma and malignant plasma cell neoplasms


plasmacytoma: Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations.

Data source
Hospital Discharge registry ICD-10: C90
Cause of Death registry ICD-10: C90
Level in the ICD-hierarchy 3
First defined in version DF2
DOID 3721
GWAS catalog 0006738
MESH D010954
SNOMED CT 415112005

Key figures

Sex All Female Male
Number of individuals 325 156 169
Unadjusted prevalence (%) 0.25 0.21 0.29
Mean age at first event (years) 65.56 64.34 66.69
Median number of events / individual 4 4 4

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 64.92 64.1 65.68
Case fatality at 5-years (%) 27.08 21.79 31.95