Childhood allergy (age < 16)

Description

atopic eczema: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Data source
FinnGen phenocode CHILDHOOD_ALLERGY
Hospital Discharge registry ICD-10: J304/J303/J3019/J450/J301/J302/L20/L236, ICD-9: 477
Cause of Death registry ICD-10: J301/L236/J302/J304/J303/J3019/J450/L20, ICD-9: 477
Pre-conditions required EVENT_AGE<16
First defined in version DF2
Ontology
DOID 3310
GWAS catalog 0000274

Key figures

Sex All Female Male
Number of individuals 1229 752 477
Unadjusted prevalence (%) 0.93 1.0 0.83
Mean age at first event (years) 8.67 8.66 8.69
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 45.32 46.54 43.4
Case fatality at 5-years (%) 0.0 0.0 0.0

Associations