Chirrosis of liver, NAS

Description

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

Data source
FinnGen phenocode CHIRHEP_NAS
Hospital Discharge registry ICD-10: K746
Cause of Death registry ICD-10: K746
First defined in version DF2
Ontology
DOID 5082
GWAS catalog 0001422
MESH D008103
SNOMED CT 19943007

Key figures

Sex All Female Male
Number of individuals 231 90 141
Unadjusted prevalence (%) 0.17 0.12 0.25
Mean age at first event (years) 62.72 61.9 63.25
Median number of events / individual 2 2 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 45.45 53.33 40.43
Case fatality at 5-years (%) 34.2 24.44 40.43

Associations