Congenital malformations of heart and great arteries

Description

pulmonary subvalvular stenosis: The obstruction of the right ventricular outflow tract that originates within the body of the right ventricle, that exists at the time of birth; it often occurs in association with other intracardiac anomalies.

Data source
FinnGen phenocode CONGEN_HEART_ARTER
Hospital Discharge registry ICD-10: Q20/Q23/Q24/Q25/Q21/Q22, ICD-9: 745/746, ICD-8: 746|747[0-3]
Cause of Death registry ICD-10: Q22/Q23/Q24/Q25/Q21/Q20, ICD-9: 745/746, ICD-8: 746|747[0-3]
First defined in version DF2
Ontology
DOID 8861
GWAS catalog 1001137
MESH D011662
SNOMED CT 204370002

Key figures

Sex All Female Male
Number of individuals 963 511 452
Unadjusted prevalence (%) 0.73 0.68 0.79
Mean age at first event (years) 34.53 33.63 35.54
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 41.33 41.88 40.71
Case fatality at 5-years (%) 1.87 0.98 2.88

Associations