Allergic purpura

Description

Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.

Data source
FinnGen phenocode D3_ALLERGPURPURA
Hospital Discharge registry ICD-10: D690, ICD-8: 2870
Cause of Death registry ICD-10: D690, ICD-8: 2870
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 11123
GWAS catalog 1000965
MESH D011695
SNOMED CT 191306005

Key figures

Sex All Female Male
Number of individuals 271 153 118
Unadjusted prevalence (%) 0.2 0.2 0.21
Mean age at first event (years) 42.59 39.88 46.1
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 31.73 32.03 31.36
Case fatality at 5-years (%) 7.38 3.92 11.86

Associations