Vitamin B12 deficiency anaemia

Description

pernicious anemia: Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.

Data source
FinnGen phenocode D3_ANAEMIA_B12_DEF
Hospital Discharge registry ICD-10: D51, ICD-8: 281[0-1]
Cause of Death registry ICD-10: D51, ICD-8: 281[0-1]
KELA reimboursements codes 107
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 13381
GWAS catalog 0005576
MESH D000752
SNOMED CT 84027009

Key figures

Sex All Female Male
Number of individuals 1034 575 459
Unadjusted prevalence (%) 0.78 0.77 0.8
Mean age at first event (years) 59.6 57.94 61.69
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 12.28 12.52 11.98
Case fatality at 5-years (%) 7.25 4.35 10.89

Associations