Hereditary factor VIII deficiency
Description
obsolete_factor VIII deficiency: An X-linked disease that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait.
Data source
| FinnGen phenocode | D3_HEREDFVIIIDEF |
| Hospital Discharge registry | ICD-10: D66, ICD-8: 2860 |
| Cause of Death registry | ICD-10: D66, ICD-8: 2860 |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 20 | 9 | 11 |
| Unadjusted prevalence (%) | 0.02 | 0.01 | 0.02 |
| Mean age at first event (years) | 36.06 | 38.38 | 34.16 |
| Median number of events / individual | 2 | 2 | 1 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 40.0 | 33.33 | 45.45 |
| Case fatality at 5-years (%) | 5.0 | 0.0 | 9.09 |