Hypersplenism

Description

hypersplenism: Overactive functioning of the spleen, resulting in excessive destruction of blood cells.

Data source
FinnGen phenocode D3_HYPERSPLENISM
Hospital Discharge registry ICD-10: D731
Cause of Death registry ICD-10: D731
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 6376
GWAS catalog 1000975
MESH D006971
SNOMED CT 58381000

Key figures

Sex All Female Male
Number of individuals 31 12 19
Unadjusted prevalence (%) 0.02 0.02 0.03
Mean age at first event (years) 56.32 54.8 57.28
Median number of events / individual 2 2 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 45.16 50.0 42.11
Case fatality at 5-years (%) 16.13 8.33 21.05

Associations