Amyloidosis, other/unspecified

Description

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Data source
FinnGen phenocode E4_AMYLNAS
Hospital Discharge registry ICD-10: E859, ICD-8: 27699
Cause of Death registry ICD-10: E859, ICD-8: 27699
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 9120
GWAS catalog 1001875
MESH D000686
SNOMED CT 17602002

Key figures

Sex All Female Male
Number of individuals 107 62 45
Unadjusted prevalence (%) 0.08 0.08 0.08
Mean age at first event (years) 59.76 57.89 62.33
Median number of events / individual 3 5 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 57.01 62.9 48.89
Case fatality at 5-years (%) 24.3 22.58 26.67

Associations