Carcinoid syndrome


carcinoid syndrome: A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)

Data source
FinnGen phenocode E4_CARCISDR
Hospital Discharge registry ICD-10: E340
Cause of Death registry ICD-10: E340
Level in the ICD-hierarchy 4
First defined in version DF2
DOID 8600
GWAS catalog 1000852
SNOMED CT 35868009

Key figures

Sex All Female Male
Number of individuals 84 46 38
Unadjusted prevalence (%) 0.06 0.06 0.07
Mean age at first event (years) 61.52 60.47 62.79
Median number of events / individual 3 4 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 65.48 67.39 63.16
Case fatality at 5-years (%) 7.14 8.7 5.26