Other disorders of glucose regulation and pancreatic internal secretion
Description
Zollinger-Ellison Syndrome: Zollinger-Ellison syndrome (ZES) is characterized by severe peptic disease (ulcers/esophageal disease) caused by hypergastrinemia secondary to a gastrinoma resulting in increased gastric acid secretion.
Data source
| FinnGen phenocode | E4_GLUCOPANCREAS |
| Hospital Discharge registry | ICD-10: E16/E15 |
| Cause of Death registry | ICD-10: E16/E15 |
| Include | E4_HYPOCOMA, E4_HYPODRUG, E4_HYPOGLYC, E4_GLUCAGONPLUS, E4_ABNGASTRIN, E4_PANCSECNAS |
| Level in the ICD-hierarchy | 2 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 778 | 386 | 392 |
| Unadjusted prevalence (%) | 0.59 | 0.51 | 0.68 |
| Mean age at first event (years) | 45.47 | 43.9 | 47.02 |
| Median number of events / individual | 1 | 1 | 1 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 10.03 | 12.18 | 7.91 |
| Case fatality at 5-years (%) | 14.78 | 10.36 | 19.13 |