Hyperfunction of pituitary gland

Description

inappropriate ADH syndrome: A syndrome characterized by abnormal secretion of antidiuretic hormone in conjunction with neoplastic growth occurring anywhere in the body.

Data source
FinnGen phenocode E4_HYPERPIT
Hospital Discharge registry ICD-10: E22
Cause of Death registry ICD-10: E22
Include E4_ACROMEG, E4_HYPERPRO, E4_ANTIDIU, E4_HYPERPITNAS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 3401
GWAS catalog 1000982
MESH D007177
SNOMED CT 55004003

Key figures

Sex All Female Male
Number of individuals 404 327 77
Unadjusted prevalence (%) 0.3 0.44 0.13
Mean age at first event (years) 40.18 38.01 49.38
Median number of events / individual 2 2 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 51.49 49.54 59.74
Case fatality at 5-years (%) 1.24 0.92 2.6

Associations