Autoimmune thyroiditis


autoimmune thyroid disease: Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis.

Data source
FinnGen phenocode E4_THYROIDITAUTOIM
Hospital Discharge registry ICD-10: E063
Cause of Death registry ICD-10: E063
Level in the ICD-hierarchy 3
First defined in version DF2
DOID 7188
GWAS catalog 0006812
MESH D013967

Key figures

Sex All Female Male
Number of individuals 140 120 20
Unadjusted prevalence (%) 0.11 0.16 0.03
Mean age at first event (years) 42.41 42.37 42.63
Median number of events / individual 2 1 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 42.14 40.83 50.0
Case fatality at 5-years (%) 0.71 0.83 0.0