Thyrotoxicosis, other and/or unspecified


Thyrotoxicosis: A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.

Data source
FinnGen phenocode E4_THYTOXNAS
Hospital Discharge registry ICD-10: E054/E055/E059, ICD-8: 2422
Cause of Death registry ICD-10: E054/E055/E059, ICD-8: 2422
Medicine purchases: ATC codes H03B
Level in the ICD-hierarchy 3
First defined in version DF2
DOID 7997
GWAS catalog 0009190
MESH D013971
SNOMED CT 90739004

Key figures

Sex All Female Male
Number of individuals 1961 1581 380
Unadjusted prevalence (%) 1.48 2.1 0.66
Mean age at first event (years) 52.94 52.37 55.32
Median number of events / individual 3 3 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 69.4 69.07 70.79
Case fatality at 5-years (%) 3.06 3.04 3.16