Schizophrenia, schizotypal and delusional disorders

Description

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Data source
FinnGen phenocode F5_SCHIZO
Hospital Discharge registry ICD-10: F20
Cause of Death registry ICD-10: F20
Include F5_SCHZPHR, F5_SCHIZOTYP, F5_DELUSIO, F5_PSYTRANS, F5_INDUDEL, F5_SCHIZOAFF, F5_PSYCHOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 5419
GWAS catalog 0000692
SNOMED CT 58214004

Key figures

Sex All Female Male
Number of individuals 5762 2936 2826
Unadjusted prevalence (%) 4.35 3.91 4.92
Mean age at first event (years) 33.8 35.28 32.26
Median number of events / individual 9 8 10

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 71.45 68.9 74.1
Case fatality at 5-years (%) 1.7 1.43 1.98

Associations