Alcohol induced polyneuropathy

Description

alcoholic neuropathy: A condition where damage to the peripheral nervous system (including the peripheral elements of the autonomic nervous system) is associated with chronic ingestion of alcoholic beverages. The disorder may be caused by a direct effect of alcohol, an associated nutritional deficiency, or a combination of factors. Clinical manifestations include variable degrees of weakness; ATROPHY; PARESTHESIAS; pain; loss of reflexes; sensory loss; diaphoresis; and postural hypotension. (From Arch Neurol 1995;52(1):45-51; Adams et al., Principles of Neurology, 6th ed, p1146)

Data source
FinnGen phenocode G6_ALCOPOLY
Hospital Discharge registry ICD-10: G621, ICD-9: 3575A
Cause of Death registry ICD-10: G621, ICD-9: 3575A
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 14183
GWAS catalog 1000803
MESH D020269
SNOMED CT 7916009

Key figures

Sex All Female Male
Number of individuals 78 10 68
Unadjusted prevalence (%) 0.06 0.01 0.12
Mean age at first event (years) 55.21 52.54 55.6
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 29.49 20.0 30.88
Case fatality at 5-years (%) 21.79 10.0 23.53

Associations