Circumscribed brain atrophy

Description

Pick disease: A rare neurodegenerative disorder leading to dementia. It is characterized by frontotemporal lobar degeneration with accumulation of tau proteins which form Pick bodies.

Data source
FinnGen phenocode G6_ATROPHCIRCUM
Hospital Discharge registry ICD-10: G310, ICD-8: 34791
Cause of Death registry ICD-10: G310
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 11870
GWAS catalog 0003096
MESH D020774
SNOMED CT 13092008

Key figures

Sex All Female Male
Number of individuals 153 74 79
Unadjusted prevalence (%) 0.12 0.1 0.14
Mean age at first event (years) 60.58 62.85 58.45
Median number of events / individual 1 1 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 37.25 29.73 44.3
Case fatality at 5-years (%) 25.49 22.97 27.85

Associations