Cerebral palsy and other paralytic syndromes

Description

Brown-Sequard Syndrome: Brown-Sequard syndrome is a rare neurological condition that results from an injury or damage to one side of the spinal cord . This condition results in weakness or paralysis on one side of the body (hemiparaplegia) and a loss of sensation on the opposite side (hemianesthesia). Brown-Sequard syndrome most commonly occurs in the the thoracic spine (upper and middle back). There are several causes of Brown-Sequard syndrome, including: a spinal cord tumor, trauma (such as a puncture wound to the neck or back), infectious or inflammatory diseases ( tuberculosis or multiple sclerosis ), and disk herniation . Treatment for this condition varies depending on the underlying cause.

Data source
FinnGen phenocode G6_CPETAL
Include G6_CP, G6_HEMIPLE, G6_PARDIPLE, G6_TETRAPLE, G6_MONOPLE, G6_CAUDA, G6_LOCKEDIN, G6_PARALOTHUNS
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 606
GWAS catalog 1001279
MESH D018437
SNOMED CT 27982003

Key figures

Sex All Female Male
Number of individuals 1025 559 466
Unadjusted prevalence (%) 0.77 0.74 0.81
Mean age at first event (years) 47.45 45.83 49.39
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 28.68 30.23 26.82
Case fatality at 5-years (%) 9.46 6.62 12.88

Associations