Other acute disseminated demyelination

Description

neuromyelitis optica: Neuromyelitis optica (NMO) and NMO spectrum disorders are inflammatory demyelinating diseases of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis (ON) and acute myelitis.

Data source
FinnGen phenocode G6_DISSOTH
Hospital Discharge registry ICD-10: G36, ICD-8: 34101
Cause of Death registry ICD-10: G36, ICD-8: 34101
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 8869
GWAS catalog 0004256
MESH D009471
SNOMED CT 25044007

Key figures

Sex All Female Male
Number of individuals 78 58 20
Unadjusted prevalence (%) 0.06 0.08 0.03
Mean age at first event (years) 41.05 38.53 48.33
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 29.49 29.31 30.0
Case fatality at 5-years (%) 3.85 1.72 10.0

Associations