Normal-pressure hydrocephalus

Description

normal pressure hydrocephalus: A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see gait disorders, neurologic), progressive intellectual decline, and urinary incontinence. Spinal fluid pressure tends to be in the high normal range. This condition may result from processes which interfere with the absorption of csf including subarachnoid hemorrhage, chronic meningitis, and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp631-3)

Data source
FinnGen phenocode G6_HCNP
Hospital Discharge registry ICD-10: G912
Cause of Death registry ICD-10: G912
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 1572
GWAS catalog 1001065
MESH D006850
SNOMED CT 30753002

Key figures

Sex All Female Male
Number of individuals 187 98 89
Unadjusted prevalence (%) 0.14 0.13 0.15
Mean age at first event (years) 68.1 69.17 66.93
Median number of events / individual 2 3 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 59.36 63.27 55.06
Case fatality at 5-years (%) 10.16 8.16 12.36

Associations