MS-disease / Multiple Sclerosis

Description

multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Data source
FinnGen phenocode G6_MS
Hospital Discharge registry ICD-10: G35, ICD-9: 340, ICD-8: 34099
Cause of Death registry ICD-10: G35, ICD-9: 340, ICD-8: 34099
KELA reimboursements codes 109
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2377
GWAS catalog 0003885
MESH D009103
SNOMED CT 24700007

Key figures

Sex All Female Male
Number of individuals 579 436 143
Unadjusted prevalence (%) 0.44 0.58 0.25
Mean age at first event (years) 41.69 40.02 46.77
Median number of events / individual 14 14 12

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 78.24 80.28 72.03
Case fatality at 5-years (%) 1.9 0.92 4.9

Event distributions

Associations