Parkinson's disease

Description

Parkinson's disease: A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.

Data source
FinnGen phenocode G6_PARKINSON
Hospital Discharge registry ICD-10: G20, ICD-9: 3320A, ICD-8: 34200
Cause of Death registry ICD-10: G20, ICD-9: 3320A, ICD-8: 34200
KELA reimboursements codes 110
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 14330
GWAS catalog 0002508
MESH D010300
SNOMED CT 49049000

Key figures

Sex All Female Male
Number of individuals 1223 555 668
Unadjusted prevalence (%) 0.92 0.74 1.16
Mean age at first event (years) 66.25 66.76 65.83
Median number of events / individual 6 5 6

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 68.85 66.31 70.96
Case fatality at 5-years (%) 12.26 11.89 12.57

Event distributions

Associations