Diabetic retinopathy

Description

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Data source
FinnGen phenocode H7_RETINOPATHYDIAB
Include H7_RETINOPATHYDIAB_BKG, H7_MACULOPATHYDIAB, H7_RETINOPATHYDIAB_BKG_SEVERE, H7_RETINOPATHYDIAB_PROLIF, H7_RETINOPATHYDIAB_ADVANC, H7_RETINOPATHYDIAB_CONSEQ, H7_RETINOPATHYDIAB_NAS
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 8947
GWAS catalog 0003770
MESH D003930
SNOMED CT 4855003

Key figures

Sex All Female Male
Number of individuals 2319 1039 1280
Unadjusted prevalence (%) 1.75 1.38 2.23
Mean age at first event (years) 48.73 47.63 49.62
Median number of events / individual 5 5 6

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 65.03 64.1 65.78
Case fatality at 5-years (%) 7.5 7.22 7.73

Associations