Atherosclerosis, excluding cerebral, coronary and PAD

Description

arteriolosclerosis: The thickening of the wall of the small arteries and arterioles. It is caused by deposition of hyaline material in the wall or concentric smooth muscle wall hypertrophy. It results in lumen narrowing and tissue ischemia. [ NCI ]

Data source
FinnGen phenocode I9_ATHSCLE
Hospital Discharge registry ICD-10: I70, ICD-9: 440, ICD-8: 440
Cause of Death registry ICD-10: I70, ICD-9: 440, ICD-8: 440
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 5162
GWAS catalog 1000819
MESH D050379

Key figures

Sex All Female Male
Number of individuals 3986 1499 2487
Unadjusted prevalence (%) 3.01 2.0 4.33
Mean age at first event (years) 66.94 68.7 65.88
Median number of events / individual 2 2 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 56.67 53.7 58.46
Case fatality at 5-years (%) 19.34 19.88 19.02

Associations