Cerebral amyloid angiopathy

Description

cerebral amyloid angiopathy: Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia.

Data source
FinnGen phenocode I9_CEREBAMY
Hospital Discharge registry ICD-10: I680
Cause of Death registry ICD-10: I680
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9246
GWAS catalog 0006790
MESH D016657
SNOMED CT 230724001

Key figures

Sex All Female Male
Number of individuals 11 N/A 8
Unadjusted prevalence (%) 0.01 N/A 0.01
Mean age at first event (years) 64.6 N/A 68.57
Median number of events / individual 1 N/A 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 9.09 N/A 12.5
Case fatality at 5-years (%) 18.18 N/A 12.5

Associations