Cerebral atherosclerosis


cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Data source
FinnGen phenocode I9_CEREBATHER
Hospital Discharge registry ICD-10: I672, ICD-8: 437
Cause of Death registry ICD-10: I672, ICD-8: 437
First defined in version DF2
DOID 12720
GWAS catalog 1000860
SNOMED CT 55382008

Key figures

Sex All Female Male
Number of individuals 78 37 41
Unadjusted prevalence (%) 0.06 0.05 0.07
Mean age at first event (years) 69.13 69.06 69.19
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 10.26 8.11 12.2
Case fatality at 5-years (%) 37.18 32.43 41.46