Thromboangiitis obliterans

Description

thromboangiitis obliterans: Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.

Data source
FinnGen phenocode I9_THROMBANG
Hospital Discharge registry ICD-10: I731, ICD-9: 4431A, ICD-8: 44310
Cause of Death registry ICD-10: I731, ICD-9: 4431A, ICD-8: 44310
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 12918
GWAS catalog 1001211
MESH D013919
SNOMED CT 52403007

Key figures

Sex All Female Male
Number of individuals 25 14 11
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 44.47 44.76 44.11
Median number of events / individual 1 1 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 24.0 14.29 36.36
Case fatality at 5-years (%) 0.0 0.0 0.0

Associations