Vascular syndromes of brain in cerebrovascular disorders

Description

lateral medullary syndrome: INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)

Data source
FinnGen phenocode I9_VASCSYND
First defined in version DF2
Ontology
DOID 3522
GWAS catalog 1001011
MESH D014854
SNOMED CT 78569004

Key figures

Sex All Female Male
Number of individuals 386 175 211
Unadjusted prevalence (%) 0.29 0.23 0.37
Mean age at first event (years) 66.39 67.71 65.29
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 19.95 21.71 18.48
Case fatality at 5-years (%) 13.73 14.29 13.27

Associations