Asthma

Description

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Data source
FinnGen phenocode J10_ASTHMA
Hospital Discharge registry ICD-10: J45/J46, ICD-9: 493, ICD-8: 493
Cause of Death registry ICD-10: J46/J45, ICD-9: 493, ICD-8: 493
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2841
GWAS catalog 0000270
MESH D001249
SNOMED CT 31387002

Key figures

Sex All Female Male
Number of individuals 12099 7445 4654
Unadjusted prevalence (%) 9.13 9.91 8.11
Mean age at first event (years) 45.41 45.22 45.73
Median number of events / individual 3 3 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 58.84 59.89 57.16
Case fatality at 5-years (%) 3.33 2.55 4.58

Event distributions

Associations