Emphysema

Description

emphysema: A subcategory of chronic obstructive pulmonary disease (COPD). It occurs in people who smoke and suffer from chronic bronchitis. It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing.

Data source
FinnGen phenocode J10_EMPHYSEMA
Hospital Discharge registry ICD-10: J43, ICD-9: 492, ICD-8: 492
Cause of Death registry ICD-10: J43, ICD-9: 492, ICD-8: 492
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 9675
GWAS catalog 0000464
MESH D004646, D011656
SNOMED CT 87433001

Key figures

Sex All Female Male
Number of individuals 386 118 268
Unadjusted prevalence (%) 0.29 0.16 0.47
Mean age at first event (years) 63.76 60.54 65.19
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 30.05 27.12 31.34
Case fatality at 5-years (%) 25.13 18.64 27.99

Associations