Pulmonary eosinophilia, not elsewhere classified

Description

eosinophilic pneumonia: An inflammatory lung disorder characterized by an increased number of eosinophils in the lungs. The majority of cases are idiopathic, without identifiable cause. In a minority of cases, medications, fungal infections, and environmental triggers have been implicated. It manifests as acute or chronic. Acute eosinophilic pneumonia is a severe and rapidly progressing pneumonia that may lead to respiratory failure requiring mechanical ventilation. Chronic eosinophilic pneumonia follows a slower course and manifests as fever, dyspnea, cough, and weight loss.

Data source
FinnGen phenocode J10_PULMEOS
Hospital Discharge registry ICD-10: J82, ICD-8: 51920
Cause of Death registry ICD-10: J82, ICD-8: 51920
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 5870
GWAS catalog 0007257

Key figures

Sex All Female Male
Number of individuals 117 77 40
Unadjusted prevalence (%) 0.09 0.1 0.07
Mean age at first event (years) 55.94 54.94 57.87
Median number of events / individual 2 3 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 53.85 58.44 45.0
Case fatality at 5-years (%) 3.42 1.3 7.5

Associations