Barret oesophagus

Description

Barrett's esophagus: Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)

Data source
FinnGen phenocode K11_BARRET
Hospital Discharge registry ICD-10: K227, ICD-9: 5301B
Cause of Death registry ICD-10: K227, ICD-9: 5301B
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9206
GWAS catalog 0000280
MESH D001471
SNOMED CT 196609006

Key figures

Sex All Female Male
Number of individuals 261 101 160
Unadjusted prevalence (%) 0.2 0.13 0.28
Mean age at first event (years) 63.45 63.92 63.16
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 19.92 14.85 23.13
Case fatality at 5-years (%) 4.98 0.99 7.5

Associations