Fibrosis and chirrhosis of liver
Description
primary biliary cirrhosis: Primary biliary cholangitis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.
Data source
| FinnGen phenocode | K11_FIBROCHIRLIV |
| Hospital Discharge registry | ICD-10: K74, ICD-8: 5719 |
| Cause of Death registry | ICD-10: K74, ICD-8: 5719 |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 409 | 228 | 181 |
| Unadjusted prevalence (%) | 0.31 | 0.3 | 0.32 |
| Mean age at first event (years) | 59.52 | 58.29 | 61.07 |
| Median number of events / individual | 2 | 4 | 2 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 55.26 | 66.23 | 41.44 |
| Case fatality at 5-years (%) | 21.76 | 12.28 | 33.7 |