Hernia

Description

congenital diaphragmatic hernia: Congenital diaphragmatic hernia (CDH) is a posterolateral defect of the diaphragm that allows passage of abdominal viscera into the thorax, leading to respiratory insufficiency and persistent pulmonary hypertension with high mortality.

Data source
FinnGen phenocode K11_HERNIA
Include K11_HERING, K11_FEMHER, K11_UMBHER, K11_VENTHER, K11_DIAHER, K11_OTHABDHER
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 3827
GWAS catalog 0007216

Key figures

Sex All Female Male
Number of individuals 17076 5381 11695
Unadjusted prevalence (%) 12.88 7.16 20.37
Mean age at first event (years) 50.78 50.87 50.73
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 28.0 25.94 28.95
Case fatality at 5-years (%) 2.61 2.66 2.58

Event distributions

Associations