Ulcerative colitis (Aki's strict definition, require KELA, min 2 HDR)

Description

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Data source
FinnGen phenocode K11_UC_STRICT2
Hospital Discharge registry ICD-10: K51, ICD-9: 556, ICD-8: 5631|569
Hospital Discharge registry: exclude ICD-9 5564A
Cause of Death registry ICD-10: K51, ICD-9: 556, ICD-8: 5631|569
Cause of Death registry: exclude ICD-9 5564A
Conditions required K11_KELAUC&K11_ULCER_NEVT>1
Level in the ICD-hierarchy C
First defined in version DF3
Ontology
DOID 8577
GWAS catalog 0000729
MESH D003093
SNOMED CT 64766004

Key figures

Sex All Female Male
Number of individuals 2250 1202 1048
Unadjusted prevalence (%) 1.7 1.6 1.83
Mean age at first event (years) 43.71 42.38 45.24
Median number of events / individual 4 4 5

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 60.62 58.24 63.36
Case fatality at 5-years (%) 1.73 1.5 2.0

Event distributions

Associations