Allergic urticaria

Description

allergic urticaria: commonly referred to as hives, is a kind of skin rash notable for pale red, raised, itchy bumps. Hives may cause a burning or stinging sensation. Histamine and other proinflammatory substances are released from mast cells in the skin and tissues in response to the binding of allergen-bound IgE antibodies to high-affinity cell surface receptors. Basophils and other inflammatory cells are also seen to release histamine and other mediators, and are thought to play an important role, especially in chronic urticarial diseases.

Data source
FinnGen phenocode L12_URTICA_ALLERG
Hospital Discharge registry ICD-10: L500
Cause of Death registry ICD-10: L500
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 10612
GWAS catalog 1000669
SNOMED CT 40178009

Key figures

Sex All Female Male
Number of individuals 672 484 188
Unadjusted prevalence (%) 0.51 0.64 0.33
Mean age at first event (years) 42.8 43.12 41.97
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 8.63 8.26 9.57
Case fatality at 5-years (%) 1.49 1.45 1.6

Associations